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Nafarelin acetate(76932-56-4 free base)

CAS No. 76932-60-0

Nafarelin acetate(76932-56-4 free base) ( RS-94991-298; Nafarelin acetate hydrate; Synarel )

Catalog No. M24772 CAS No. 76932-60-0

Nafarelin acetate is a GnRH agonist that acts as an analog of GnRH. Nafarelin causes a decrease in the pituitary secretion of gonadotropins luteinizing hormone (LH) and follicle-stimulating hormone (FSH).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Nafarelin acetate(76932-56-4 free base)
  • Note
    Research use only, not for human use.
  • Brief Description
    Nafarelin acetate is a GnRH agonist that acts as an analog of GnRH. Nafarelin causes a decrease in the pituitary secretion of gonadotropins luteinizing hormone (LH) and follicle-stimulating hormone (FSH).
  • Description
    Nafarelin acetate is a GnRH agonist that acts as an analog of GnRH. Nafarelin causes a decrease in the pituitary secretion of gonadotropins luteinizing hormone (LH) and follicle-stimulating hormone (FSH). It may be used in the treatment of estrogen-dependent conditions.
  • Synonyms
    RS-94991-298; Nafarelin acetate hydrate; Synarel
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    GNRHR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    76932-60-0
  • Formula Weight
    1400.6
  • Molecular Formula
    C68H89N17O16
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:Soluble; Water:Insoluble
  • SMILES
    CC(C)C[C@@H](C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N)NC(=O)[C@@H](CC2=CC3=CC=CC=C3C=C2)NC(=O)[C@H](CC4=CC=C(C=C4)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC5=CNC6=CC=CC=C65)NC(=O)[C@H](CC7=CN=CN7)NC(=O)[C@@H]8CCC(=O)N8.CC(=O)O.O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Ludwig C, Desmoulins PO, Driancourt MA, Goericke-Pesch S, Hoffmann B. Reversible downregulation of endocrine and germinative testicular function (hormonal castration) in the dog with the GnRH-agonist azagly-nafarelin as a removable implant "Gonazon"; a preclinical trial. Theriogenology. 2009 Apr 15;71(7):1037-45.
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